NIH Awards $168M Contract to Icahn School of Medicine for Biodefense Immunity Modeling

Contract Overview

Contract Amount: $16,812,225 ($16.8M)

Contractor: Icahn School of Medicine AT Mount Sinai

Awarding Agency: Department of Health and Human Services

Start Date: 2005-09-29

End Date: 2010-09-29

Contract Duration: 1,826 days

Daily Burn Rate: $9.2K/day

Competition Type: FULL AND OPEN COMPETITION

Number of Offers Received: 7

Pricing Type: COST NO FEE

Sector: R&D

Official Description: MODELING IMMUNITY FOR BIODEFENSE

Place of Performance

Location: NEW YORK, NEW YORK County, NEW YORK, 10029

State: New York Government Spending

Plain-Language Summary

Department of Health and Human Services obligated $16.8 million to ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI for work described as: MODELING IMMUNITY FOR BIODEFENSE Key points: 1. Significant investment in biodefense research, focusing on modeling immunity. 2. Contract awarded via full and open competition, suggesting a competitive process. 3. Long-term contract (5 years) indicates a sustained need for this research. 4. Potential for breakthroughs in understanding and combating biological threats.

Value Assessment

Rating: good

The contract type is 'COST NO FEE', which is common for research and development where costs are reimbursed but no profit is made. The award amount of $168M over 5 years suggests a substantial but potentially reasonable investment for the scope of R&D.

Cost Per Unit: N/A

Competition Analysis

Competition Level: full-and-open

The contract was awarded using full and open competition, indicating that multiple vendors had the opportunity to bid. This method generally promotes price discovery and ensures the government receives competitive pricing.

Taxpayer Impact: Taxpayer funds are being invested in critical biodefense research, aiming to enhance national security and public health preparedness.

Public Impact

Enhances national security by advancing biodefense capabilities. Supports cutting-edge scientific research in immunology and infectious diseases. Potential to develop new strategies for vaccines and treatments against biological threats. Fosters collaboration between government and academic research institutions.

Waste & Efficiency Indicators

Waste Risk Score: 50 / 10

Warning Flags

Positive Signals

Sector Analysis

This contract falls under Research and Development in the Physical, Engineering, and Life Sciences (NAICS 541710). Spending in this sector is crucial for innovation and addressing complex challenges like biodefense, with significant government investment typically seen in areas with high societal impact.

Small Business Impact

The data does not indicate whether small businesses were involved in this contract. Full and open competition allows for participation, but the nature of large-scale R&D contracts often favors established research institutions.

Oversight & Accountability

The National Institutes of Health (NIH) is responsible for overseeing this contract. Standard government oversight mechanisms for R&D contracts, including progress reports and milestone reviews, would be in place to ensure accountability and effective use of funds.

Related Government Programs

Risk Flags

Tags

research-and-development-in-the-physical, department-of-health-and-human-services, ny, definitive-contract, 10m-plus

Frequently Asked Questions

What is this federal contract paying for?

Department of Health and Human Services awarded $16.8 million to ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI. MODELING IMMUNITY FOR BIODEFENSE

Who is the contractor on this award?

The obligated recipient is ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI.

Which agency awarded this contract?

Awarding agency: Department of Health and Human Services (National Institutes of Health).

What is the total obligated amount?

The obligated amount is $16.8 million.

What is the period of performance?

Start: 2005-09-29. End: 2010-09-29.

What specific biological threats does this immunity modeling aim to address, and how will the research translate into actionable biodefense strategies?

The research likely focuses on understanding the complex immune responses to various pathogens relevant to biodefense, such as viruses and bacteria. The goal is to identify key immunological mechanisms that confer protection or susceptibility. This knowledge can then inform the development of novel vaccines, therapeutics, and diagnostic tools, ultimately strengthening the nation's preparedness and response capabilities against biological attacks or naturally occurring outbreaks.

Given the 'COST NO FEE' contract type, what are the primary mechanisms for ensuring the research remains on track and delivers value without a profit motive driving efficiency?

The 'COST NO FEE' structure is typical for basic research where outcomes are uncertain. Value is ensured through rigorous scientific oversight by NIH program managers, adherence to detailed research plans and milestones, regular progress reporting, and peer review of findings. The absence of a fee shifts the focus from profit to scientific advancement and fulfilling the research objectives outlined in the contract.

How will the effectiveness of the immunity modeling be measured, and what are the key performance indicators for this long-term R&D effort?

Effectiveness will likely be measured by the scientific validity and impact of the research findings, such as publications in high-impact journals, successful prediction of immune responses, and the development of novel hypotheses or experimental models. Key performance indicators could include the successful completion of research phases, the generation of predictive models that are validated experimentally, and the contribution of the research to broader biodefense initiatives and public health preparedness goals.

Industry Classification

NAICS: Professional, Scientific, and Technical ServicesScientific Research and Development ServicesResearch and Development in the Physical, Engineering, and Life Sciences

Product/Service Code: RESEARCH AND DEVELOPMENTN – Health R&D Services

Competition & Pricing

Extent Competed: FULL AND OPEN COMPETITION

Solicitation Procedures: NEGOTIATED PROPOSAL/QUOTE

Offers Received: 7

Pricing Type: COST NO FEE (S)

Evaluated Preference: NONE

Contractor Details

Parent Company: Mount Sinai Hospital

Address: 1 GUSTAVE L LEVY PL, NEW YORK, NY, 10029

Business Categories: Category Business, Educational Institution, Higher Education, Nonprofit Organization, Not Designated a Small Business

Financial Breakdown

Contract Ceiling: $23,517,489

Exercised Options: $20,310,652

Current Obligation: $16,812,225

Contract Characteristics

Multi-Year Contract: Yes

Commercial Item: COMMERCIAL ITEM PROCEDURES NOT USED

Timeline

Start Date: 2005-09-29

Current End Date: 2010-09-29

Potential End Date: 2010-09-29 00:00:00

Last Modified: 2024-11-23

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