NHLBI awards $4.8M to Broad Institute for TOPMED Omics Resource, ensuring centralized data analysis
Contract Overview
Contract Amount: $4,811,972 ($4.8M)
Contractor: THE Broad Institute, Inc
Awarding Agency: Department of Health and Human Services
Start Date: 2025-09-26
End Date: 2026-09-25
Contract Duration: 364 days
Daily Burn Rate: $13.2K/day
Competition Type: FULL AND OPEN COMPETITION
Pricing Type: FIRM FIXED PRICE
Sector: R&D
Official Description: NHLBI TRANS-OMICS FOR PRECISION MEDICINE (TOPMED) FOR THE CENTRALIZED OMICS RESOURCE (CORE)
Place of Performance
Location: CAMBRIDGE, MIDDLESEX County, MASSACHUSETTS, 02142
Plain-Language Summary
Department of Health and Human Services obligated $4.8 million to THE BROAD INSTITUTE, INC for work described as: NHLBI TRANS-OMICS FOR PRECISION MEDICINE (TOPMED) FOR THE CENTRALIZED OMICS RESOURCE (CORE) Key points: 1. The contract focuses on a critical need for centralized omics data analysis within the TOPMED program. 2. Broad Institute is a leading genomics research institution, suggesting strong technical capability. 3. The award is a delivery order under an existing contract, implying some level of pre-qualification. 4. Potential risks include reliance on a single entity for a critical resource and data security.
Value Assessment
Rating: good
The award amount of $4.8M for a 1-year period appears reasonable for a specialized omics resource. Benchmarking against similar large-scale data analysis contracts would provide further context.
Cost Per Unit: N/A
Competition Analysis
Competition Level: full-and-open
The contract was awarded under full and open competition, which is positive for price discovery. However, as a delivery order, the specific competition details for this order are not detailed.
Taxpayer Impact: Full and open competition aims to secure the best value for taxpayers by encouraging multiple bids and competitive pricing.
Public Impact
Enhances precision medicine research by providing a centralized omics data resource. Supports the TOPMED program's goal of understanding the genetic basis of cardiovascular, pulmonary, and sleep diseases. Facilitates data sharing and collaboration among researchers, accelerating scientific discovery.
Waste & Efficiency Indicators
Waste Risk Score: 50 / 10
Warning Flags
- Potential vendor lock-in for a critical resource.
- Data security and privacy concerns for sensitive omics data.
Positive Signals
- Leverages expertise of a leading research institution.
- Centralized resource promotes data standardization and accessibility.
Sector Analysis
This contract falls within the scientific research and development sector, specifically focusing on advanced biological data analysis. Spending in this area is crucial for medical breakthroughs and public health initiatives.
Small Business Impact
The data does not indicate any specific provisions or set-asides for small businesses in this award. Further analysis would be needed to determine if small businesses were involved as subcontractors.
Oversight & Accountability
As a delivery order under an existing contract, oversight may be integrated into the broader contract management framework. Clear performance metrics and reporting requirements are essential.
Related Government Programs
- Testing Laboratories and Services
- Department of Health and Human Services Contracting
- National Institutes of Health Programs
Risk Flags
- Reliance on a single entity for a critical function.
- Potential for data security breaches with sensitive omics data.
- Scalability challenges if research needs exceed initial projections.
- Long-term sustainability of the centralized resource beyond the contract period.
Tags
testing-laboratories-and-services, department-of-health-and-human-services, ma, delivery-order, 1m-plus
Frequently Asked Questions
What is this federal contract paying for?
Department of Health and Human Services awarded $4.8 million to THE BROAD INSTITUTE, INC. NHLBI TRANS-OMICS FOR PRECISION MEDICINE (TOPMED) FOR THE CENTRALIZED OMICS RESOURCE (CORE)
Who is the contractor on this award?
The obligated recipient is THE BROAD INSTITUTE, INC.
Which agency awarded this contract?
Awarding agency: Department of Health and Human Services (National Institutes of Health).
What is the total obligated amount?
The obligated amount is $4.8 million.
What is the period of performance?
Start: 2025-09-26. End: 2026-09-25.
What is the specific value proposition of a centralized omics resource compared to decentralized approaches for the TOPMED program?
A centralized omics resource offers significant value by standardizing data processing, ensuring consistency in analysis, and facilitating easier data sharing and integration across different research cohorts. This reduces redundancy, improves data quality, and accelerates the discovery of complex biological patterns relevant to precision medicine.
What are the primary risks associated with relying on a single vendor for the centralized omics resource, and how are they mitigated?
The primary risk is vendor lock-in and potential disruption if the vendor fails to perform. Mitigation strategies include robust contract performance monitoring, clear service level agreements, contingency planning for data transfer, and potentially fostering competition for future iterations of the resource.
How does this contract contribute to the overall effectiveness and efficiency of the TOPMED program's research goals?
This contract directly enhances the effectiveness of the TOPMED program by providing a dedicated, expert-managed resource for complex omics data. This efficiency allows researchers to focus on biological interpretation rather than data infrastructure, accelerating the identification of genetic factors and leading to more impactful precision medicine discoveries.
Industry Classification
NAICS: Professional, Scientific, and Technical Services › Architectural, Engineering, and Related Services › Testing Laboratories and Services
Product/Service Code: SPECIAL STUDIES/ANALYSIS, NOT R&D › SPECIAL STUDIES - NOT R and D
Competition & Pricing
Extent Competed: FULL AND OPEN COMPETITION
Solicitation Procedures: NEGOTIATED PROPOSAL/QUOTE
Pricing Type: FIRM FIXED PRICE (J)
Evaluated Preference: NONE
Contractor Details
Address: 415 MAIN ST, CAMBRIDGE, MA, 02142
Business Categories: Category Business, Corporate Entity Tax Exempt, Nonprofit Organization, Not Designated a Small Business, Special Designations, U.S.-Owned Business
Financial Breakdown
Contract Ceiling: $23,370,909
Exercised Options: $4,811,972
Current Obligation: $4,811,972
Contract Characteristics
Commercial Item: COMMERCIAL PRODUCTS/SERVICES PROCEDURES NOT USED
Cost or Pricing Data: NO
Parent Contract
Parent Award PIID: 75N92023D00013
IDV Type: IDC
Timeline
Start Date: 2025-09-26
Current End Date: 2026-09-25
Potential End Date: 2026-09-25 00:00:00
Last Modified: 2026-04-02
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