NIH Awards $2.9M Contract for Large Molecule Drug Toxicology Research to IIT Research Institute
Contract Overview
Contract Amount: $2,902,988 ($2.9M)
Contractor: IIT Research Institute
Awarding Agency: Department of Health and Human Services
Start Date: 2022-04-01
End Date: 2027-03-31
Contract Duration: 1,825 days
Daily Burn Rate: $1.6K/day
Competition Type: FULL AND OPEN COMPETITION
Number of Offers Received: 4
Pricing Type: COST PLUS FIXED FEE
Sector: R&D
Official Description: PRECLINICAL TOXICOLOGY OF LARGE MOLECULE DRUGS DEVELOPED FOR CANCER AND OTHER INDICATIONS
Place of Performance
Location: CHICAGO, COOK County, ILLINOIS, 60616
State: Illinois Government Spending
Plain-Language Summary
Department of Health and Human Services obligated $2.9 million to IIT RESEARCH INSTITUTE for work described as: PRECLINICAL TOXICOLOGY OF LARGE MOLECULE DRUGS DEVELOPED FOR CANCER AND OTHER INDICATIONS Key points: 1. Contract focuses on preclinical toxicology for cancer and other indications. 2. IIT Research Institute is the sole awardee. 3. Potential for significant impact on future drug development and patient outcomes. 4. Spending falls within the Research and Development sector.
Value Assessment
Rating: fair
The contract type is Cost Plus Fixed Fee, which can lead to higher costs if not managed carefully. Benchmarking against similar toxicology studies is difficult without more specific cost data.
Cost Per Unit: N/A
Competition Analysis
Competition Level: full-and-open
The contract was awarded under full and open competition, suggesting a competitive bidding process. However, the specific pricing outcomes of this competition are not detailed.
Taxpayer Impact: Taxpayer funds are supporting critical early-stage drug research, with the potential for future health benefits and economic returns if successful.
Public Impact
Supports the development of new treatments for serious diseases like cancer. Advances scientific understanding of large molecule drug safety. Potential for job creation within the research and development sector.
Waste & Efficiency Indicators
Waste Risk Score: 50 / 10
Warning Flags
- Cost Plus Fixed Fee contract type can incentivize higher spending.
- Limited transparency on specific cost drivers for toxicology studies.
- Long contract duration may increase cost escalation risks.
Positive Signals
- Supports critical medical research with high potential impact.
- Awarded through full and open competition.
- Long-term investment in health innovation.
Sector Analysis
This contract falls under Research and Development in the Physical, Engineering, and Life Sciences. Spending in this sector is crucial for innovation but can be subject to long development cycles and uncertain outcomes.
Small Business Impact
This contract was not awarded to a small business. Opportunities for small businesses may exist as subcontractors or in future related procurements.
Oversight & Accountability
The National Institutes of Health (NIH) is responsible for overseeing this contract. Standard oversight mechanisms for research contracts should be in place to ensure progress and responsible spending.
Related Government Programs
- Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Department of Health and Human Services Contracting
- National Institutes of Health Programs
Risk Flags
- Cost Plus Fixed Fee contract structure.
- Long contract duration.
- Lack of specific cost per unit data.
- Potential for scope creep in research projects.
Tags
research-and-development-in-the-physical, department-of-health-and-human-services, il, definitive-contract, 1m-plus
Frequently Asked Questions
What is this federal contract paying for?
Department of Health and Human Services awarded $2.9 million to IIT RESEARCH INSTITUTE. PRECLINICAL TOXICOLOGY OF LARGE MOLECULE DRUGS DEVELOPED FOR CANCER AND OTHER INDICATIONS
Who is the contractor on this award?
The obligated recipient is IIT RESEARCH INSTITUTE.
Which agency awarded this contract?
Awarding agency: Department of Health and Human Services (National Institutes of Health).
What is the total obligated amount?
The obligated amount is $2.9 million.
What is the period of performance?
Start: 2022-04-01. End: 2027-03-31.
What is the projected cost per toxicology study or per drug candidate?
The provided data does not specify the cost per toxicology study or per drug candidate. The total award amount of $2,902,988 covers the entire contract duration and scope. Detailed cost breakdowns would be necessary to assess the efficiency of individual study costs.
What are the key performance indicators (KPIs) for this contract to ensure research effectiveness?
Key performance indicators are not explicitly detailed in the provided summary. Typically, for such research contracts, KPIs would include timely completion of preclinical toxicology reports, adherence to scientific protocols, achievement of specific research milestones, and the quality of data generated for regulatory submissions.
How will the success of this research translate into tangible public health benefits?
The success of this research, specifically the preclinical toxicology of large molecule drugs, is a critical step in the drug development pipeline. Positive results would enable the progression of promising drug candidates to clinical trials, potentially leading to new, more effective treatments for cancer and other diseases, ultimately improving public health outcomes.
Industry Classification
NAICS: Professional, Scientific, and Technical Services › Scientific Research and Development Services › Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
Product/Service Code: RESEARCH AND DEVELOPMENT › N – Health R&D Services
Competition & Pricing
Extent Competed: FULL AND OPEN COMPETITION
Solicitation Procedures: NEGOTIATED PROPOSAL/QUOTE
Offers Received: 4
Pricing Type: COST PLUS FIXED FEE (U)
Evaluated Preference: NONE
Contractor Details
Address: 10 W 35TH ST FL 4, CHICAGO, IL, 60616
Business Categories: Category Business, Corporate Entity Tax Exempt, Nonprofit Organization, Not Designated a Small Business, Special Designations, U.S.-Owned Business
Financial Breakdown
Contract Ceiling: $9,353,817
Exercised Options: $3,174,256
Current Obligation: $2,902,988
Actual Outlays: $2,620,698
Contract Characteristics
Commercial Item: COMMERCIAL PRODUCTS/SERVICES PROCEDURES NOT USED
Cost or Pricing Data: NO
Timeline
Start Date: 2022-04-01
Current End Date: 2027-03-31
Potential End Date: 2029-03-31 00:00:00
Last Modified: 2026-03-27
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